Publications

The acrorhagial response of the sea anemone Anthopleura krebsi. M.S. Thesis, Florida State University, 1976.
Actinian acrorhagi: their form and function in aggression.  Ph.D. Dissertation, Florida State University, 1978.

Invertebrate Behavioral Physiology, Cytology and Sensory Receptors

Bigger, C.H. (1976) The acrorhagial response in Anthopleura krebsi: intraspecific and interspecific recognition. In:  Coelenterate          
               Ecology and Behavior (Proceedings of the Third International Symposium on Coelenterate Biology), pp. 127-136, 
               Plenum Press,  New York.

Mariscal, R.N. and Bigger, C.H. (1976) A comparison of putative sensory receptors associated with nematocysts in an anthozoan 
               and a scyphozoan. In: Coelenterate Ecology and Behavior (Proceedings of the third International Symposium on 
               Coelenterate Biology), pp. 559-568.

Mariscal, R.N., Bigger, C.H. and McLean, R. (1976) The form and function of cnidarian spirocysts. I. Ultrastructure of the 
               capsule exterior and relationship to the tentacle sensory surface. Cell Tiss. Res. 168: 465-474.

Conklin, E., Bigger, C.H., and Mariscal, R.N. (1977) The formation and taxonomic status of the microbasic q-mastigophore nematocyst 
              of sea anemones. Biol. Bull. 152: 159-168.

Mariscal, R.N. and Bigger, C.H. (1977) Possible ecological significance of octocoral epithelial ultrastructure. Proc. of the Third             
              Internatl. Symp. on Coral Reefs, pp. 127-133, Rosenstiel School of Marine and Atmospheric Science, University of Miami.

Mariscal, R.N., Conklin, E. and Bigger, C.H. (1977) The ptychocyst, a major new category of cnida used in tube construction by a           
              cerianthid anemone. Biol. Bull. 152: 392-405.

Mariscal, R.N., Conklin, E., and Bigger, C.H. (1978) The putative sensory receptors associated with the cnidae of cnidarians. 
              Scanning Electron Microscopy/1978, Vol. II - An International Review of Advances in Biomedical Applications of the             
              SEM, IIT Research Institute, pp. 959-966.

Sicarello, L., Minasian, L.L., Bigger, C.H., and Mariscal, R.N. (1979) Asexual reproduction in scyphistomae of Cassiopea 
               xamachana (Scyphozoa:Rhizostoma): Exogenous effects and the interaction of budding and strobilation. Amer. Zool.
              19: 985 (Abstr.).

Bigger, C.H. (1980) Interspecific and intraspecific acrorhagial aggressive behavior among sea anemones, a recognition of self and 
              not-self. Biol. Bull. 159: 117-134.

Bigger, C.H. (1982) Sea anemone aggression, recognition of self and not-self in a lower invertebrate. The 1982 McGraw-Hill 
              Yearbook of Science and Technology, McGraw-Hill, Inc., pp. 403-406.

Bigger, C.H. (1982) The cellular basis of the aggressive acrorhagial response of sea anemones.  J. Morph. 173: 259-278

Comparative Immunology

Hildemann, W.H., Bigger, C.H., and Johnston, I.S. (1979) Histoincompatibility reactions and allogeneic polymorphism among 
              invertebrates. Transplantation Proceedings 11: 1136 - 1141.

Bigger, C.H. and Runyan, R. (1979) An in situ demonstration of self-recognition in gorgonians.  Developmental and Comparative 
              Immunology 3: 591-597.

Hildemann, W.H., Bigger, C.H., Jokiel, P.L. and Johnston, I.S.(1980) Characteristics of  immune memory in invertebrates.  
              Immunological Memory (M.J. Manning, ed.) Elsevier/North Holland, pp. 9-14.

Hildemann, W.H., Jokiel, P.L., Bigger, C.H., and Johnston, I.S. (1980) Allogeneic polymorphism and alloimmune memory in the coral, 
                Montipora verrucosa. Transplantation 30: 297-301.

Hildemann, W.H., Bigger, C.H., Johnston, I.S., and Jokiel, P.L. (1980) Characteristics of transplantation immunity in the sponge, 
               Callyspongia diffusa. Transplantation 30:362-367.

Johnston, I.S., Jokiel, P.L., Bigger, C.H., and Hildemann, W.H. (1981) The influence of temperature on the kinetics of allograft 
              reactions in a tropical sponge and a reef coral.  Biol. Bull. 160: 280-291.

Bigger, C.H., Hildemann, W.H., Jokiel, P.L., and Johnston, I.S. (1981) Afferent sensitization vs. efferent cytotoxicity in allogeneic 
              tissue responses of the marine sponge Callyspongia diffusa. Transplantation 31: 461-464.

Bigger, C.H. and Hildemann, W.H. (1982) Cellular defense systems of the Coelenterata. Chapter 3, in The Reticuloendothelial System 
              (N. Cohen and M. Sigel, eds.), Plenum Press, New York, pp. 59-87.

Bigger, C.H. and Hildemann, W.H. (1982) Leukocytes of the sea star Dermasterias imbricata.  Proceedings of the 1981 International 
              Echinoderms Conference.  p. 355 (Abstr.).

Bigger, C.H., Jokiel, P.L., Hildemann, W.H., and Johnston, I.S. (1982)  Characterization of alloimmune memory in a sponge. J. 
              Immunol. 129: 1570-1572.

Jokiel, P.L., Hildemann, W.H., and Bigger, C.H. (1982) Frequency of intercolony graft acceptance or rejection as a measure of 
              population structure in the sponge Callyspongia diffusa. Marine Biol. 71:  135-l39.

Bigger, C.H., Jokiel, P.L. and Hildemann, W.H. (1983) Cytotoxic transplantation immunity in the sponge, Toxadocia violacea. 
               Transplantation 35: 239-243.

Jokiel, P.L., Hildemann, W.H., and Bigger, C.H. (1983) Clonal population structure of two sympatric species of the reef coral 
                Montipora. Bull. Mar. Sci. 33: 181-187.

Smith, L.C., I.S. Johnston, Bigger, C.H. and Hildemann, W.H. (1983) Cellular reorganization during allograft rejection in the Hawaiian 
               sponge Callyspongia diffusa. Amer. Zool. 23:900 (Abstr.).

Smith, L.C., Bigger, C.H., Johnston, I.S., Jokiel, P.L. and Hildemann,W.H. (1984) Transplantation immunity in the Hawaiian sponge 
                Callyspongia diffusa. Develop. Comp.  Immunol. Sup. 3:45 (Abstr).

Bigger, C.H. and Hildemann, W.H. (1984) Leukocytes and their ontogeny in the sea star Dermasterias imbricata. Develop. Comp. 
               Immunol. Sup. 3:85 (Abstr).

Van de Vyver, G. and Bigger, C.H. (1984) Mediators: lectins, agglutinins, lysins and complement II. Develop. Comp. Immunol. Sup. 
               3:191-192 (Summary).

Bigger, C.H. (1984) Immunorecognition among invertebrates, Develop. Comp. Immunol. Sup. 3:29-34.

Sasaki, N., Yoneda, K., Bigger, C., Brown, J., and Mullen, Y. (1984) Fetal pancreas transplant in miniature swine. 1.  Developmental 
              characteristics of fetal pig pancreases, Transplantation 38:335-340.

Smith, L.C., I.S. Johnston, Bigger, C.H., and Hildemann, W.H. (1984) Allograft rejection in  Callyspongia diffusa, a Hawaiian sponge. 
              A model system. Fed. Proc. 43:1985 (Abstr.)

Bigger, C.H. (1988) Historecognition and immunocompetence in selected marine invertebrates. in Invertebrate Historecognition (R. 
              Grosberg, D. Hedgecock and K. Nelson,eds.) Plenum Press, New York, pp. 55-65.

Bigger, C.H. (1988) The nematocyst role in anthozoan aggression.  The Biology of the Nematocyst, D. Hessinger & H. Lenhoff, eds.) 
              Academic Press, New York, pp. 295-308.

Bigger, C.H., L.M. Peixoto and C.T. Olano (1989) Aspects of alloimmunity in the gorgonian Swiftia exserta. Dev. Comp. Immunol. 
              13:385 (Abstr).

Ramirez, D.L. and C.H. Bigger (1989) Alloimmunity in a marine sponge, Haliclona aquaeductus.   Dev. Comp. Immunol. 
              13:340-341 (Abstr.).

Salter-Cid, L. and C.H. Bigger (1991) Alloimmunity in the gorgonian coral Swiftia exserta. Biol.  Bull. 181:127-134.

Bigger, C.H. (1991) Characteristics and distribution of the leukocytes of the sea star Dermasterias imbricata. Amer.  Zool. 
              31:101A (Abstr.).

Bigger, C.H. and C. Olano (1991) Cellular aspects of alloimmune responses of the gorgonian coral, Swiftia exserta. Dev. Comp. 
              Immunol. 15(sl):599 (Abstr.)

Bigger, C.H. and C. Olano (1993) Alloimmune cellular responses of the gorgonian coral Swiftia exserta. J. Immunol. 150:134A (Abstr.).

Zuniga, A.A., C. Olano and C.H. Bigger (1994) A simplified dehydrating and clearing procedure for sponges and corals. J. 
              Histotechnology 17:  55-57.

Jokiel, P.L. and C.H. Bigger (1994)  Aspects of histocompatibility and regeneration in the solitary reef coral Fungia scutaria.  Biol. 
              Bull. 186:  72-80.

Bigger, C.H. and C.T. Olano (1994)  Alloimmune responses of the gorgonian coral Swiftia exserta..  Develop. Comp. Immunol. 
              18(Sup 1):  S111 (Abstr.).

Meszaros, A. and C.H. Bigger (1994)  Light effects on wound healing in a soft coral.  Develop. Comp. Immunol.  18(Sup 1): 
              S148 (Abstr.).

Bossart, G.D. and C.H. Bigger (1994)  The cellular components of the nonspecific, humoral and cell-mediated immune systems in the 
              peripheral blood of the West Indian Manatee (Trichechus manatus latirostris), cellular population dynamics in health and 
              disease.  First International Manatee and Dugong Research Conference (Abstr.).

Cirroco, R.E., C. Bigger, M. Renart, and G. Bossart (1997)  Cytokine analysis in Atlantic bottlenose dolphins.  Develop. Comp. 
              Immunol. 21(2):  190. (Abstr.)

Maloney, B. and C. H. Bigger (1997) Analysis of sponge mortality in Florida Bay.  Develop.  Comp. Immunol. 21(2): 126. (Abstr.)

Meszaros, A. and C.H. Bigger (1999) Qualitative and quantitative study of wound healing processes in the coelenterate, Plexaurella 
               fusifera: spatial, temporal, and environmental (light attenuation) influences.  J. Invert. Pathology 73:  321-331.

Olano, C.T. & C.H. Bigger. Phagocytic activities of the gorgonian coral Swiftia exserta. (2000) J.   Invert. Pathology 76: 176-184.  

Dishaw, L.J., S.L.  Smith and C.H. Bigger (2000) sequence analysis of partial cDNA clones from a primitive coral, encoding a 
              thiolester-containing protein. Develop. Comp. Immunol. 24: S23. (Abstr.) 

Bigger, C.H., L. Dishaw and C. Olano (2000) Immune defenses of the gorgonian coral, Swiftia exserta, simple or complex?  Develop. 
              Comp. Immunol.  24: S43. (Abstr.)  

Shaffer, C., C. Bigger, C. Beck  and A. Shope (2000) The effect of salinity stress on the wound healing rate of Plexaurella fusifera, a 
              soft coral from the near shore waters of the Florida Keys.  Develop. Comp. Immunol.  24: S46. (Abstr.)  

Cirocco, R.E. and C. Bigger (2000) Molecular cytokine analysis in Atlantic bottlenose dolphins: Messenger RNA 
              characterization in lymphoid cells.  Develop. Comp. Immunol.  24:  S61. (Abstr.)

Dishaw, S. Smith & C. Bigger, (2001) Sequence and phylogenetic analysis of partial cDNA clones from a coral, encoding a 
              thiolester-containing A2M/C3 –like protein.  FASEB Journal 15: A686. (Abstr.)

Shaffer, C., C. Bigger, C. Beck and A. Shope (2001) Effect of salinity stress on wound healing in Plexaurella fusifera, a soft 
              coral.  FASEB Journal 15: A692.  (Abstr.)