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Expression of NMDAR subunit NR-1 in lithium-treated
and estrogen-treated mouse hippocampal cells using RT-PCR.
The goal of our study is to investigate a possible
synergistic relationship between lithium and estrogen
in protecting neurons from death and preserving function.
The specific aim of my project towards this goal is
to investigate the effects that lithium and estrogen,
together, have on the expression of NMDAR NR-1receptor
subunits. The study uses RT-PCR and immunocytochemical
methods for analyzing primary mixed cultures of C57BL6J
mice hippocampal cells following treatment with lithium
and estrogen.
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