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Back to the Table of Alginate Genes
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1. |
Aarons, S. J., I. W. Sutherland, A. M.
Chakrabarty, and M. P. Gallagher. 1997. A novel gene, algK, from
the alginate biosynthesis cluster of Pseudomonas aeruginosa. Microbiology.
143:641-652. |
2. |
Baynham, P. J., and D. J. Wozniak. 1996. Identification
and characterization of AlgZ, an AlgT-dependent DNA-binding
protein required for Pseudomonas aeruginosa algD transcription. Mol
Microbiol. 22:97-108. |
3. |
Berry, A., J. D. DeVault, S. Roychoudhury, N. A. Zielinski, T. B. May,
E. C. Wynne, R. K. Rothmel, A. M. Fialho, M. Husseinb, V. Krylov, and
A. M. Chakrabarty. 1988. Pseudomonas aeruginosa infection in cystic
fibrosis: molecular approaches to a medical problem. CHIMICAoggi. 9:13-19. |
4. |
Boucher, J. C., J. Martinez-Salazar, M. J. Schurr, M. H. Mudd, H. Yu,
and V. Deretic. 1996. Two distinct loci affecting conversion to mucoidy
in Pseudomonas aeruginosa in cystic fibrosis encode homologs of
the serine protease HtrA. J. Bacteriol. 178:511-523. |
5. |
Boucher, J. C., M. J. Schurr, H. Yu, D. W. Rowen, and V. Deretic. 1997. Pseudomonas aeruginosa in cystic fibrosis: role of mucC in the regulation of alginate production and stress sensitivity. Microbiology 1997 Nov;143( Pt 11):3473-3480. 143:3473-3480. |
6. |
Chitnis, C. E., and D. E. Ohman. 1990. Cloning of Pseudomonas aeruginosa
algG, which controls alginate structure. J. Bacteriol. 172:2894-2900. |
7. |
Chu, L., T. B. May, A. M. Chakrabarty, and T. K. Misra. 1991. Nucleotide
sequence and expression of the algE gene involved in alginate biosynthesis
by Pseudomonas aeruginosa. Gene. 107:1-10. |
8. |
Coyne, M. J., Jr., K. S. Russell, C. L. Coyle, and J. B. Goldberg. 1994.
The Pseudomonas aeruginosa algC gene encodes phosphoglucomutase,
required for the synthesis of a complete lipopolysaccharide core. J. Bacteriol. 176:3500-3507. |
9. |
Darzins, A., and A. M. Chakrabarty. 1984. Cloning of genes controlling
alginate biosynthesis from a mucoid cystic fibrosis isolate of Pseudomonas
aeruginosa. J. Bacteriol. 159:9-18. |
10. |
Darzins, A., B. Frantz, R. I. Vanags, and A. M. Chakrabarty. 1986. Nucleotide
sequence analysis of the phosphomannose isomerase gene (pmi) of Pseudomonas aeruginosa and comparison with the corresponding Escherichia
coli gene manA. Gene. 42:293-302. |
11. |
Darzins, A., S.-K. Wang, R. I. Vanags, and A. M. Chakrabarty. 1985. Clustering
of mutations affecting alginic acid biosynthesis in mucoid Pseudomonas
aeruginosa. J. Bacteriol. 164:516-524. |
12. |
Deretic, V., R. Dikshit, M. Konyecsni, A. M. Chakrabarty, and T. K. Misra.
1989. The algR gene, which regulates mucoidy in Pseudomonas
aeruginosa, belongs to a class of environmentally responsive genes. J. Bacteriol. 171:1278-1283. |
13. |
Deretic, V., J. F. Gill, and A. M. Chakrabarty. 1987. Gene algD coding
for GDP mannose dehydrogenase is transcriptionally activated in mucoid Pseudomonas aeruginosa. J. Bacteriol. 169:351-358. |
14. |
Deretic, V., J. F. Gill, and A. M. Chakrabarty. 1987. Pseudomonas
aeruginosa infection in cystic fibrosis: nucleotide sequence and transcriptional
regulation of the algD gene. Nucleic Acids Res. 11:4567-4581. |
15. |
Deretic, V., and W. M. Konyecsni. 1989. Control of mucoidy in Pseudomonas
aeruginosa: transcriptional regulation of algR and identification
of the second regulatory gene, algQ. J. Bacteriol. 171:3680-3688. |
16. |
DeVault, J. D., A. Berry, T. K. Misra, A. Darzins, and A. M. Chakrabarty.
1989. Environmental sensory signals and microbial pathogenesis: Pseudomonas
aeruginosa infection in cystic fibrosis. Bio/Technology. 7:352-357. |
17. |
DeVries, C. A., and D. E. Ohman. 1994. Mucoid-to-nonmucoid conversion
in alginate-producing Pseudomonas aeruginosa often results from
spontaneous mutations in algT, encoding a putative alternative
sigma factor, and shows evidence for autoregulation. J. Bacteriol. 176:6677-6687. |
18. |
Flynn, J. L., and D. E. Ohman. 1988. Cloning of genes from mucoid Pseudomonas
aeruginosa which control spontaneous conversion to the alginate production
phenotype. J. Bacteriol. 170:1452-1460. |
19. |
Flynn, J. L., and D. E. Ohman. 1988. Use of a gene replacement cosmid
vector for cloning alginate conversion genes from mucoid and nonmucoid Pseudomonas aeruginosa strains: algS controls expression of algT. J. Bacteriol. 170:3228-3236. |
20. |
Franklin, M. J., C. E. Chitnis, P. Gacesa, A. Sonesson, D. C. White,
and D. E. Ohman. 1994. Pseudomonas aeruginosa AlgG is a
polymer level alginate C5-mannuronan epimerase. J. Bacteriol. 176:1821-1830. |
21. |
Franklin, M. J., and D. E. Ohman. 1993. Identification of algF in the alginate biosynthetic gene cluster of Pseudomonas aeruginosa which is required for alginate acetylation. J. Bacteriol. 175:5057-5065. |
22. |
Franklin, M. J., and D. E. Ohman. 1996. Identification of algI and algJ in the Pseudomonas aeruginosa alginate biosynthetic gene
cluster which are required for alginate O acetylation. J. Bacteriol. 178:2186-2195. |
23. |
Fyfe, J. A., and J. R. Govan. 1980. Alginate synthesis in mucoid Pseudomonas
aeruginosa: a chromosomal locus involved in control. J. Gen. Microbiol.
119:443-450. |
24. |
Fyfe, J. A. M., and J. R. W. Govan. 1981. A revised chromosomal location
for muc: a locus involved in the control of alginate production
by mucoid Pseudomonas aeruginosa. Soc. Gen. Microbiol. Q. 8:250-251. |
25. |
Goldberg, J. B., and T. Dahnke. 1992. Pseudomonas aeruginosa AlgB,
which modulates the expression of alginate, is a member of the NtrC subclass
of prokaryotic regulators. Mol. Microbiol. 6:59-66. |
26. |
Goldberg, J. B., W. L. Gorman, J. L. Flynn, and D. E. Ohman. 1993. A
mutation in algN permits trans activation of alginate production
by algT in Pseudomonas species. J. Bacteriol. 175:1303-1308. |
27. |
Goldberg, J. B., K. Hatano, and G. B. Pier. 1993. Synthesis of lipopolysaccharide
O side chains by Pseudomonas aeruginosa PAO1 requires the enzyme
phosphomannomutase. J. Bacteriol. 175:1605-1611. |
28. |
Goldberg, J. B., and D. E. Ohman. 1984.
Cloning and expression in Pseudomonas aeruginosa of a gene involved
in the production of alginate. J. Bacteriol. 158:1115-1121. |
29. |
Goldberg, J. B., and D. E. Ohman. 1987. Construction and characterization
of Pseudomonas aeruginosa algB mutants: role of algB in
high-level production of alginate. J. Bacteriol. 169:1593-1602. |
30. |
Hershberger, C. D., R. W. Ye, M. R. Parsek, Z. Xie,
and A. M. Chakrabarty. 1995. The algT (algU) gene of Pseudomonas
aeruginosa, a key regulator involved in alginate biosynthesis, encodes
an alternative s factor (sE).
Proc. Natl. Acad. Sci. USA. 92:7941-7945. |
31. |
Jain, S., and D. E. Ohman. 1998. Deletion of algK in mucoid Pseudomona aeruginosa blocks alginate polymer formation
and results in uronic acid secretion. J Bacteriol. 180:634-641. |
32. |
Kato, J., L. Chu, K. Kitano, J. D. DeVault, K. Kimbara,
A. M. Chakrabarty, and T. K. Misra. 1989. Nucleotide sequence of a regulatory
region controlling alginate synthesis in Pseudomonas aeruginosa:
characterization of the algR2 gene. Gene. 84:31 38. |
33. |
Kato, J., T. K. Misra, and A. M. Chakrabarty. 1990.
AlgR3, a protein resembling eukaryotic histone H1, regulates alginate synthesis
in Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. USA. 87:2887-2891. |
34. |
Konyecsni, W. M., and V. Deretic. 1990. DNA sequence
and expression analysis of algP and algQ, components of the
multigene system transcriptionally regulating mucoidy in Pseudomonas
aeruginosa: algP contains multiple direct repeats. J. Bacteriol. 172:2511-2520. |
35. |
Ma, S., D. J. Wozniak, and D. E. Ohman. 1997. Identification
of the histidine protein kinase KinB in Pseudomonas aeruginosa and
its phosphorylation of the alginate regulator AlgB. J Biol Chem. 272:17952-17960. |
36. |
Maharaj, R., T. B. May, S. K. Wang, and
A. M. Chakrabarty. 1993. Sequence of the alg8 and alg44 genes
involved in the synthesis of alginate by Pseudomonas aeruginosa.
Gene. 136:267-269. |
37. |
Martin, D. W., B. W. Holloway, and V. Deretic. 1993.
Characterization of a locus determining the mucoid status of Pseudomonas
aeruginosa: AlgU shows sequence similarities with a Bacillus sigma factor. J. Bacteriol. 175:1153-1164. |
38. |
Martin, D. W., M. J. Schurr, M. H. Mudd, and V. Deretic.
1993. Differentiation of Pseudomonas aeruginosa into the alginate-producing
form: inactivation of mucB causes conversion to mucoidy. Mol. Microbiol. 9:497-506. |
39. |
Martin, D. W., M. J. Schurr, M. H. Mudd,
J. R. Govan, B. W. Holloway, and V. Deretic. 1993. Mechanism of conversion
to mucoidy in Pseudmonas aeruginosa infecting cystic fibrosis patients.
Proc. Natl. Acad. Sci. USA. 90:8377-8381. |
40. |
Mathee, K., C. J. McPherson, and D. E. Ohman. 1997.
Posttranslational control of the algT (algU)-encoded sigma22
for expression of the alginate regulon in Pseudomonas aeruginosa and localization of its antagonist proteins MucA and MucB (AlgN). J. Bacteriol. 179:3711-3720. |
41. |
Monday, S. R., and N. L. Schiller. 1996. Alginate
synthesis in Pseudomonas aeruginosa: the role of AlgL (alginate
lyase) and AlgX. J. Bacteriol. 178:625-632. |
42. |
Ohman, D. E., J. B. Goldberg, and J. L. Flynn. 1990.
Molecular analysis of the genetic switch activating alginate production.,
p. 28-35. In S. Silver, A. M. Chakrabarty, B. Iglewski, and S. Kaplan (ed.),
Pseudomonas: biotransformations, pathogenesis, and evolving biotechnology.
Amer. Soc. Microbiol. Pub., Washington. |
43. |
Ohman, D. E., K. Mathee, C. J. McPherson, C. A. DeVries,
S. Ma, D. J. Wozniak, and M. J. Franklin. 1996. Regulation of the alginate
(algD) operon in Pseudmonas aeruginosa, p. 472-483. In T. Nakazawa,
K. Furukawa, D. Haas, and S. Silver (ed.), Molecular biology of Pseudomonads.
Amer. Soc. Microbiol., Washington, D.C. |
44. |
Padgett, P. J., and P. V. Phibbs, Jr. 1986. Phosphomannomutase
activity in wild type and alginate-producing strains of Pseudomonas aeruginosa.
Current Microbiol. 14:187-192. |
45. |
Rehm, B. H., G. Boheim, J. Tommassen, and U. K. Winkler.
1994. Overexpression of algE in Escherichia coli: subcellular
localization, purification, and ion channel properties. J. Bacteriol. 176:5639-5647. |
46. |
Roychoudhury, S., T. B. May, J. F. Gill, S. K. Singh,
D. S. Feingold, and A. M. Chakrabarty. 1989. Purification and characterization
of guanosine diphospho-D mannose dehydrogenase. A key enzyme in the biosynthesis
of alginate by Pseudomonas aeruginosa. J. Biol. Chem. 264:9380-9385. |
47. |
Roychoudhury, S., K. Sakai, and A. M. Chakrabarty.
1992. AlgR2 is an ATP/GTP-dependent protein kinase involved in alginate
synthesis by Pseudomonas aeruginosa.. Proc Natl Acad Sci U S A. 89:2659-63. |
48. |
Sá-Correia, I., A. Darzins, S.-K. Wang, A.
Berry, and A. M. Chakrabarty. 1987. Alginate biosynthetic enzymes in mucoid
and nonmucoid Pseudomonas aeruginosa: overproduction of phosphomannose
isomerase, phosphomannomutase, and GDP-mannose pyrophosphorylase by overexpression
of the phosphomannose isomerase (pmi) gene. J. Bacteriol. 169:3224-3231. |
49. |
Schlictman, D., M. Kubo, S. Shankar, and A. M. Chakrabarty.
1995. Regulation of nucleoside diphosphate kinase and secretable virulence
factors in Pseudomonas aeruginosa: roles of algR2 and algH.
J. Bacteriol. 177:2469-74. |
50. |
Schurr, M. J., D. W. Martin, M. H. Mudd, and V. Deretic.
1994. Gene cluster controlling conversion to alginate-overproducing phenotype
in Pseudomonas aeruginosa: Functional analysis in a heterologous
host and role in the instability of mucoidy. J. Bacteriol. 176:3375-3382. |
51. |
Schurr, M. J., H. Yu, J. M. Martinez-Salazar, J.
C. Boucher, and V. Deretic. 1996. Control of AlgU, a member of the sE-like family of stress sigma factors, by the negative
regulators MucA and MucB and Pseudomonas aeruginosa conversion
to mucoidy in cystic fibrosis. J. Bacteriol. 178:4997-5004. |
52. |
Schurr, M. J., H. Yu, J. M. Martinez-Salazar, N.
S. Hibler, and V. Deretic. 1995. Biochemical characterization and posttranslational
modification of AlgU, a regulator of stress response in Pseudomonas
aeruginosa. Biochem. Biophys. Res. Commun. 216:874-880. |
53. |
Shinabarger, D., A. Berry, T. B. May, R. Rothmel,
A. Fialho, and A. M. Chakrabarty. 1991. Purification and characterization
of phosphomannose isomerase-guanosine diphospho-D-mannose pyrophosphorylase
&emdash; a bifunctional enzyme in the alginate biosynthetic pathway of Pseudomonas
aeruginosa. J. Biol. Chem. 266:2080-2088. |
54. |
Shinabarger, D., T. B. May, A. Boyd, M. Ghosh, and
A. M. Chakrabarty. 1993. Nucleotide sequence and expression of the Pseudomonas
aeruginosa algF gene controlling acetylation of alginate. Mol. Microbiol. 9:1027-35. |
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Wang, S.-K., I. Sa'-Correia, A. Darzins,
and A. M. Chakrabarty. 1987. Characterization of the Pseudomonas aeruginosa alginate (alg) gene region II. J. Gen. Microbiol. 133:2301-2314. |
56. |
Whitchurch, C. B., R. A. Alm, and J. S. Mattick.
1996. The alginate regulator AlgR and an associated sensor FimS are required for twitching motility in Pseudomonas aeruginosa.
Proc. Natl. Acad. Sci. U S A. 93:9839-9843. |
57. |
Wozniak, D. J., and D. E. Ohman. 1991. Pseudomonas
aeruginosa AlgB, a two component response regulator of the NtrC
family, is required for algD transcription. J. Bacteriol. 173:1406-1413. |
58. |
Xie, Z. D., C. D. Hershberger, S. Shankar, R. W.
Ye, and A. M. Chakrabarty. 1996. Sigma factor&endash;anti-sigma factor interaction
in alginate synthesis: inhibition of AlgT by MucA. J. Bacteriol. 178:4990-4996. |
59. |
Ye, R. W., N. A. Zielinski, and A. M. Chakrabarty.
1994. Purification and characterization of phosphomannomutase/phosphoglucomutase
from Pseudomonas aeruginosa involved in biosynthesis of both alginate
and lipopolysaccharide. J Bacteriol. 176:4851-7. |
60. |
Yu, H., M. Mudd, J. C. Boucher, M. J. Schurr, and
V. Deretic. 1997. Identification of the algZ gene upstream of the
response regulator algR and its participation in control of alginate
production in Pseudomonas aeruginosa. J Bacteriol. 179:187-193. |
61. |
Zielinski, N. A., A. M. Chakrabarty, and A. Berry.
1991. Characterization and regulation of the Pseudomonas aeruginosa algC gene encoding phosphomannomutase. J. Biol. Chem. 266:9754-9763. |
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