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After its establishment,
and with the growth in research in Biological
Sciences and Environmental
Studies, the Preserve has become a resource for research at FIU. Organisms
in the Preserve are sources of materials that yield secondary compounds
for analysis of their distribution and chemistry, and yield samples of
DNA for sequencing and phylogenetic analysis.
For instance, David Lee, sampled the distribution of anthocyanins in plants
of the Preserve. This provided part of the database that led to publications,
listed below. Scientists in the Center
for Ethnobiology and Natural Products (CENaP, established by support
from the National Institutes of Health) at FIU, have taken advantage of
plants in the Preserve representative of the unusual tropical flora of
South Florida to analyze materials for the presence of natural products
(secondary compounds) with unusual biological activities.
Over the past year CENaP scientists have been collecting and extracting
hundreds of plant samples from the FIU preserve, and are initiating biological
evaluation of these extracts, looking for activity against pathogenic
fungi and bacteria, antibiotic resistant organisms as well as potential
bioterrorist agents. In collaboration with Miami Children's Hospital,
CENaP is also screening plant extracts for potential immunomodulators,
cancer chemotherapeutic and chemopreventive agents.
Once a plant extract has shown promising biological activity, fractionation
and chemical evaluation of biologically active plant extracts takes place.
This is important to both understanding the mechanism of action, as well
as to identify the active phytoconstituent(s) of an extract. The preserve
contains a number of plants that are known and used traditionally by the
Miccosukee tribe. CENaP director Brad Bennett has worked extensively with
Mikosukee elders, and has documented a significant amount of Mikosukee
traditional plant lore. In the face of eroding traditional knowledge and
practices, the potential of the preserve as a force for conservation of
traditional plants and plant knowledge is significant.
BIBLIOGRAPHY
Lee, D.W. and T.M. Collins.
2001. Phylogenetic and ontogenetic influences on the
distribution of anthocyanins and betacyanins in leaves of tropical plants.
International Journal
of Plant Science 162:1141-1153.
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